February 7, 2025Open Access

Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis

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Resumen

Among adults with active lupus nephritis, obinutuzumab plus standard therapy was more efficacious than standard therapy alone in providing a complete renal response. (Funded by F. Hoffmann-La Roche; REGENCY ClinicalTrials.gov number, NCT04221477.).

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Cite This Study

Furie et al. (Fri,) studied this question.

synapsesocial.com/papers/69d7ca08319e71454dbeda46 https://doi.org/https://doi.org/10.1056/nejmoa2410965

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Kidney Outcomes and Preservation of Kidney Function With Obinutuzumab in Patients With Lupus Nephritis: A Post Hoc Analysis of the <scp>NOBILITY</scp> Trial2023 · 46 citations
2POS0529 OBINUTUZUMAB BENEFITS PATIENTS WITH ACTIVE LUPUS NEPHRITIS IRRESPECTIVE OF BASELINE PROTEINURIA SEVERITY: A POST HOC ANALYSIS OF THE PHASE II NOBILITY TRIAL2024 · 1 citations
3A New Equation to Estimate Glomerular Filtration Rate2009 · 25,724 citations
4Change in Albuminuria and GFR as End Points for Clinical Trials in Early Stages of CKD: A Scientific Workshop Sponsored by the National Kidney Foundation in Collaboration With the US Food and Drug Administration and European Medicines Agency2019 · 562 citations
5Humoral and cellular responses after COVID-19 vaccination in anti-CD20-treated lymphoma patients2021 · 90 citations

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