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M-Type Phospholipase A 2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy | Synapse

July 1, 2009Open Access

M-Type Phospholipase A 2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy

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Resumen

A majority of patients with idiopathic membranous nephropathy have antibodies against a conformation-dependent epitope in PLA(2)R. PLA(2)R is present in normal podocytes and in immune deposits in patients with idiopathic membranous nephropathy, indicating that PLA(2)R is a major antigen in this disease.

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Cite This Study

Beck et al. (Wed,) studied this question.

synapsesocial.com/papers/69d7d611f39344339dd18ac9 https://doi.org/https://doi.org/10.1056/nejmoa0810457

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