Barium chloride injures myofibers through calcium-induced proteolysis with fragmentation of motor nerves and microvessels

BaCl2 injures myofibers through depolarization of the sarcolemma, causing Ca2+ overload with transient contraction, leading to proteolysis and membrane rupture. Motor innervation and capillarity appear disrupted concomitant with myofiber damage, further compromising muscle integrity.