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January 13, 2012

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Macrophages prevent hemorrhagic infarct transformation in murine stroke models

MGMichael GliemDüsseldorf University Hospital AMAnne K. MausbergEssen University Hospital JLJohn‐Ih LeeDüsseldorf University Hospital

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Resumen

Bone marrow-derived MOs/MPs recruited via CCR2 and acting via TGF-β1 are essential for maintaining integrity of the neurovascular unit following brain ischemia. Future therapies should be aimed at enhancing physiological repair functions of CCR2(+) MOs/MPs rather than blocking their hematogenous recruitment.

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Cite This Study

Gliem et al. (Fri,) studied this question.

synapsesocial.com/papers/69d8409105ee2ba81dbef535 https://doi.org/https://doi.org/10.1002/ana.23529

Macrophages prevent hemorrhagic infarct transformation in murine stroke models | Synapse

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