Does the rate of aldosterone breakthrough differ between candesartan and valsartan in hypertensive patients with diabetes mellitus?
Aldosterone breakthrough occurs equally with candesartan and valsartan in hypertensive diabetic patients, suggesting a potential role for aldosterone blockade to prevent renal injury.
Aldosterone breakthrough was seen to be equal in hypertensive patients with diabetes mellitus treated with candesartan or valsartan. Aldosterone blockade therapy may be effective in preventing renal injury in hypertensive patients with aldosterone breakthrough.
Yoneda et al. (Sat,) studied this question.
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