September 1, 2012Open Access

Amyloid‐beta oligomerization in Alzheimer dementia versus high‐pathology controls

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Resumen

The results raise the intriguing hypothesis that the linkage between plaques and oligomers may be a key pathophysiological event underlying dementia of the Alzheimer type. This Aβ oligomer assay may be useful for many tests of the oligomer hypothesis.

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Cite This Study

Esparza et al. (Sat,) studied this question.

synapsesocial.com/papers/69d87bf752654bb436d193b9 https://doi.org/https://doi.org/10.1002/ana.23748

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2Characterisation of two antibodies to oligomeric Aβ and their use in ELISAs on human brain tissue homogenates2008 · 44 citations
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4Monoclonal antibodies that target pathological assemblies of Aβ2006 · 316 citations
5Targeting Amyloid-β Peptide (Aβ) Oligomers by Passive Immunization with a Conformation-selective Monoclonal Antibody Improves Learning and Memory in Aβ Precursor Protein (APP) Transgenic Mice2005 · 257 citations

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