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Tolerance and Withdrawal From Prolonged Opioid Use in Critically Ill Children | Synapse

April 19, 2010Open Access

Tolerance and Withdrawal From Prolonged Opioid Use in Critically Ill Children

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Resumen

Opioid tolerance and withdrawal occur frequently in critically ill children. Novel insights into opioid receptor physiology and cellular biochemical changes will inform scientific approaches for the use of opioid analgesia and the prevention of opioid tolerance and withdrawal.

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Anand et al. (Mon,) studied this question.

synapsesocial.com/papers/69d8b59517a1cc0598d17f52 https://doi.org/https://doi.org/10.1542/peds.2009-0489

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