September 29, 2015Open Access

Vascular Smooth Muscle Cell Senescence Promotes Atherosclerosis and Features of Plaque Vulnerability

Puntos clave

Los puntos clave no están disponibles para este artículo en este momento.

Resumen

We conclude that plaque VSMC senescence in atherosclerosis is associated with loss of TRF2. VSMC senes cence promotes both atherosclerosis and features of plaque vulnerability, identifying prevention of senescence as a potential target for intervention.

Leer artículo completoexternamente

Me gusta

Guardar

Ver artículo completo

Cite This Study

Wang et al. (Tue,) studied this question.

synapsesocial.com/papers/69d8d82e183921ebcaae3dba https://doi.org/https://doi.org/10.1161/circulationaha.115.016457

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Proliferation in primary and restenotic coronary atherectomy tissue. Implications for antiproliferative therapy.1993 · 365 citations
2Acute coronary thrombosis--the role of plaque disruption and its initiation and prevention1995 · 127 citations
3Smooth Muscle Cells in Atherosclerosis Originate From the Local Vessel Wall and Not Circulating Progenitor Cells in ApoE Knockout Mice2006 · 236 citations
4Atherosclerosis2001 · 3,051 citations
5Healed Plaque Ruptures and Sudden Coronary Death2001 · 914 citations

Me gusta

Guardar

Ver artículo completo