Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial2008 · 1,402 citations
2. 2合成および生物学的疾患修飾性抗リウマチ薬による関節リウマチ管理に関するEULAR(欧州リウマチ学会)推奨事項: 2013年最新情報2014 · 635 citations
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4. 4Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: A randomized, controlled trial2004 · 1,165 citations
5. 5Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial2013 · 671 citations