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Biomarkers of TGF-β Signaling Pathway and Prognosis of Pancreatic Cancer | Synapse

January 20, 2014Open Access

Biomarkers of TGF-β Signaling Pathway and Prognosis of Pancreatic Cancer

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Resumen

Our data provides valuable baseline information regarding the TGF-β pathway in pancreatic cancer, which can be utilized in targeted therapy clinical trials. High TGF-β1 plasma level, SMAD4 SNP or TGF-βR2/SMAD4 tumor protein expression may suggest a dependence on this pathway in patients with advanced pancreatic cancer.

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Cite This Study

Javle et al. (Mon,) studied this question.

synapsesocial.com/papers/69d9566fc7f0c3ae80a3d0d4 https://doi.org/https://doi.org/10.1371/journal.pone.0085942