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June 9, 2005Open Access

TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT)

HKHidenori KasaiLifeArc JAJeremy AllenUC Davis Health System RMRoger M. MasonChina University of Geosciences

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Resumen

Our study shows that TGF-beta1 induces A549 alveolar epithelial cells to undergo EMT via Smad2 activation. Our data support the concept of EMT in lung epithelial cells, and suggest the need for further studies to investigate the phenomenon.

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Cite This Study

Kasai et al. (Thu,) studied this question.

synapsesocial.com/papers/69d962cb94760e72e6a3c30d https://doi.org/https://doi.org/10.1186/1465-9921-6-56

TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT) | Synapse