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Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation | Synapse

February 24, 2022Open Access

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Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation

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Resumen

These data identify BACH1 as a mechanosensor of hemodynamic stress and reveal that the BACH1-YAP transcriptional network is essential to vascular inflammation and atherogenesis. BACH1 shows potential as a novel therapeutic target in atherosclerosis.

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Cite This Study

Jia et al. (Thu,) studied this question.

synapsesocial.com/papers/69d973fb9a6164e50fa3ccf1 https://doi.org/https://doi.org/10.1161/circresaha.121.319540