April 12, 2011Open Access

IgE Mediated Autoallergy against Thyroid Peroxidase – A Novel Pathomechanism of Chronic Spontaneous Urticaria?

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Resumen

Our findings show that a sizeable subgroup of csU patients expresses IgE antibodies against thyroid peroxidase. These autoantibodies could cause "autoallergic" mast cell activation, a novel pathomechanism of chronic spontaneous urticaria.

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Cite This Study

Altrichter et al. (Tue,) studied this question.

synapsesocial.com/papers/69da16ea0f778bd2e468402b https://doi.org/https://doi.org/10.1371/journal.pone.0014794

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1A Method for Measuring Specific IgE in Sera by Direct ELISA without Interference by IgG Competition or IgG Autoantibodies to IgE2000 · 32 citations
2IgG4 and IgE are the major immunoglobulins targeting the NC 16A domain of BP 180 in bullous pemphigoid: Serum levels of these immunoglobulins reflect disease activity2000 · 37 citations
3Chronic urticaria and thyroid auto-immunity.2005 · 22 citations
4IgG4 and IgE are the major immunoglobulins targeting the NC16A domain of BP180 in bullous pemphigoid: Serum levels of these immunoglobulins reflect disease activity2000 · 172 citations
5Association of Chronic Urticaria and Angioedema With Thyroid Autoimmunity1983 · 256 citations

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