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Treatment of Thyroid Dysfunction and Serum Lipids: A Systematic Review and Meta-analysis | Synapse

September 21, 2020Open Access

Treatment of Thyroid Dysfunction and Serum Lipids: A Systematic Review and Meta-analysis

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Resumen

Treatment of overt but not subclinical hyperthyroidism is associated with worsening of the lipid profile. Levothyroxine therapy in both overt and subclinical hypothyroidism leads to improvement in the lipid profile, with a smaller magnitude of improvement in subclinical hypothyroidism.

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Cite This Study

Kotwal et al. (Mon,) studied this question.

synapsesocial.com/papers/69da250da6045d71bfa3c36a https://doi.org/https://doi.org/10.1210/clinem/dgaa672

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Reversal of Decreased Human Adipose Tissue Lipoprotein Lipase and Hypertriglyceridemia after Treatment of Hypothyroidism1976 · 79 citations
2Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT)1986 · 1,760 citations
3Treatment of Subclinical Hypothyroidism Reduces Atherogenic Lipid Levels in a Placebo-controlled Double-blind Clinical Trial2008 · 51 citations
4Dramatically Increased Intestinal Absorption of Cholesterol Following Hypophysectomy Is Normalized by Thyroid Hormone2008 · 73 citations
5Association between thyroid function and lipid profiles, apolipoproteins, and high-density lipoprotein function2017 · 84 citations