April 27, 2022Open Access

Impact of Cryopreservation and Freeze-Thawing on Therapeutic Properties of Mesenchymal Stromal/Stem Cells and Other Common Cellular Therapeutics

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Resumen

Targeted research into optimizing the cryopreservation and freeze-thawing routines and the adjunct manufacturing process design may provide crucial advantages to increase both the safety and efficacy of cellular therapeutics in clinical use and to enable effective market deployment strategies to become economically viable and sustainable medicines.

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Cite This Study

Cottle et al. (Wed,) studied this question.

synapsesocial.com/papers/69dabfd14a1e15904c83622f https://doi.org/https://doi.org/10.1007/s40778-022-00212-1

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1Guidelines for Cord Blood Unit Thaw and Infusion2020 · 10 citations
2Preclinical Evaluation of the Safety and Efficacy of Cryopreserved Bone Marrow Mesenchymal Stromal Cells for Corneal Repair2021 · 18 citations
3Dimethyl Sulfoxide: A Central Player Since the Dawn of Cryobiology, is Efficacy Balanced by Toxicity?2020 · 246 citations
4CD56 in the Immune System: More Than a Marker for Cytotoxicity?2017 · 395 citations
5Cryopreservation of human pluripotent stem cell-derived cardiomyocytes is not detrimental to their molecular and functional properties2020 · 49 citations

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