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Ultrafast Reversible Photo-Cross-Linking Reaction: Toward in Situ DNA Manipulation | Synapse

June 27, 2008

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Ultrafast Reversible Photo-Cross-Linking Reaction: Toward in Situ DNA Manipulation

YYYoshinaga YoshimuraJapan Advanced Institute of Science and Technology KFKenzo FujimotoJapan Advanced Institute of Science and Technology

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Resumen

We describe a novel ultrafast reversible DNA interstrand photo-cross-linking reaction via 3-cyanovinylcarbazole nucleoside ( (CNV)K). Oligodeoxynucleotide (ODN) containing (CNV)K can be photo-cross-linked by irradiation at 366 nm for 1 s, and the photo-cross-linked ODN can be split by irradiation at 312 nm for 60 s.

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Cite This Study

Yoshimura et al. (Fri,) studied this question.

synapsesocial.com/papers/69dae6ef4a1e15904c8369c8 https://doi.org/https://doi.org/10.1021/ol801112j

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