Histone lactylation is a key epigenetic mechanism that drives the reparative response in monocytes to facilitate cardiac repair after myocardial infarction.
Histone lactylation promotes early remote activation of the reparative transcriptional response in monocytes, which is essential for the establishment of immune homeostasis and timely activation of the cardiac repair process post-MI.
Wang et al. (Fri,) studied this question.
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