Angiomyofibroblastoma (AMFB) is a rare benign mesenchymal tumor traditionally associated with a very low rate of recurrence, typically affecting middle-aged women, with few cases documented in the literature. We report an unusual case of a 19-year-old sexually inactive female who presented with a huge vaginal AMFB. Ultrasound revealed a well-demarcated mass with internal vascularity. Magnetic resonance imaging (MRI) demonstrated mostly clear boundaries, but the margin adjacent to the right posterior urethral wall was indistinct. After surgical resection, the tumor recurred twice. This case highlights that AMFB carries a risk of recurrence and underscores the critical importance of complete tumor excision with negative margins. We also detail the sonographic and MRI features of the primary and recurrent AMFB, emphasizing the role of ultrasound in diagnosis and surveillance.
Li et al. (Thu,) studied this question.