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Mismatch Repair Deficiency, Microsatellite Instability, and Survival | Synapse

February 27, 2017Open Access

Mismatch Repair Deficiency, Microsatellite Instability, and Survival

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Resumen

In the MAGIC trial, MMRD and high MSI were associated with a positive prognostic effect in patients treated with surgery alone and a differentially negative prognostic effect in patients treated with chemotherapy. If independently validated, MSI or MMRD determined by preoperative biopsies could be used to select patients for perioperative chemotherapy.

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Cite This Study

Smyth et al. (Mon,) studied this question.

synapsesocial.com/papers/69dbdc523d9adb00e7685630 https://doi.org/https://doi.org/10.1001/jamaoncol.2016.6762

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