March 1, 2020Open Access

Phosphorylation of Tau and α-Synuclein Induced Neurodegeneration in MPTP Mouse Model of Parkinson’s Disease

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These findings revealed that p-α-Synuclein and p-Tau proteins are key pathological events leading to neurodegeneration and motor dysfunctions in the mouse MPTP model of PD. Our data suggest that the interference with the GSK3β activity may be an effective approach for the treatment of PD.

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Hu et al. (Sun,) studied this question.

synapsesocial.com/papers/69dbdfa45b363cdf1c8361a7 https://doi.org/https://doi.org/10.2147/ndt.s235562

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