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Buprenorphine for Cancer Pain—The Safest Opioid, and Patients With Cancer Cannot Get It | Synapse

June 5, 2025

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Buprenorphine for Cancer Pain—The Safest Opioid, and Patients With Cancer Cannot Get It

ACAmy A. CaseRoswell Park Comprehensive Cancer Center MDMellar P. DavisLevine Cancer Institute MCMarcin ChwistekFox Chase Cancer Center

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Resumen

This Viewpoint discusses the use of buprenorphine to treat cancer pain and difficulties in affordability and access despite its efficacy and safety compared with full-agonist opioids.

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Cite This Study

Case et al. (Thu,) studied this question.

synapsesocial.com/papers/69dc694424e766dc3135925f https://doi.org/https://doi.org/10.1001/jamaoncol.2025.1337

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Treating Chronic Pain with Buprenorphine—The Practical Guide2021 · 37 citations
2Oxycodone in the Opioid Epidemic: High ‘Liking’, ‘Wanting’, and Abuse Liability2020 · 119 citations
3Opioid addiction, diversion, and abuse in chronic and cancer pain2018 · 22 citations
4Emerging pharmacologic mechanisms of buprenorphine to explain experience of analgesia versus adverse effects2021 · 8 citations
5Opioid addiction and misuse in adult and adolescent patients with cancer2017 · 40 citations