Characterization, antifungal potential, cytocompatibility, and regenerative potential of mucoadhesive gel containing antifungal‐β‐cyclodextrin inclusion complexes

Puntos clave

• The aim is to evaluate the antifungal potential, cytocompatibility, and regenerative capacity of a mucoadhesive gel containing β-cyclodextrin inclusion complexes.
• Develop mucoadhesive gel with antifungal β-cyclodextrin inclusion complexes.
• Test gel for antifungal activity against oral candidiasis pathogens.
• Assess rheological and mucoadhesive properties of the gel.
• Evaluate cytocompatibility at therapeutic doses.
• The gel showed enhanced antifungal activity compared to noncomplexed NYS.
• Maintained favorable rheological and mucoadhesive properties.
• Demonstrated cytocompatibility at lower therapeutic doses.