Abstract: Nanotechnology is a promising field in materials science and healthcare due to its focus on engineering functional systems at the nanoscale. Advancements in nanotechnology have enabled the incorporation of therapeutic agents into nanoparticles for cancer treatment, offering benefits like increased solubility, altered pharmacokinetics, prolonged drug half-life, enhanced bioavailability, and decreased metabolism. Transdermal therapy is effective in treating localized breast and skin cancers, providing continuous low-dose chemotherapeutics, and creating cancer vaccines like cervical cancer vaccines. However, formulation design is challenging due to conjugation chemistry and the prolonged and repeatable administration of therapeutically effective dosages. UV exposure during infancy and adolescence causes basal cell carcinoma, whereas its chronic exposure in preceding decades has been attributed to the genesis of squamous cell carcinoma. Cutaneous malignant melanoma is the fastest-growing malignancy among white populations. Topical therapy is crucial for managing non-melanoma skin cancers, but inadequate drug penetration and patient compliance hinder its effectiveness. Researchers have utilized advanced delivery technologies like topical patches to address the issue of traditional topical therapies. This review introduces NMSC and discusses topical treatments, focusing on the new technology of topical patches. It explains their ability to overcome limitations of current medicines and is the first to combine all advances. Most importantly, this paper details all of the latest advances in innovative topical patches for the treatment of NMSC.
Monika et al. (Tue,) studied this question.
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