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April 1, 2005

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Antioxidant Treatment of Patients With Friedreich Ataxia

PHPaul HartRoyal Marsden Hospital RLRaffaele LodiIstituto delle Scienze Neurologiche di Bologna BRB. RajagopalanSri Ramachandra Institute of Higher Education and Research

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Resumen

This therapy resulted in sustained improvement in mitochondrial energy synthesis that was associated with a slowing of the progression of certain clinical features and a significant improvement in cardiac function.

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Cite This Study

Hart et al. (Fri,) studied this question.

synapsesocial.com/papers/69dcc757a5c75be4cfe542b4 https://doi.org/https://doi.org/10.1001/archneur.62.4.621

Also Consider

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1Idebenone treatment in Friedreich patients: One-year-long randomized placebo-controlled trial2003 · 234 citations
2Tissue concentrations of coenzyme Q10 in the rat following its oral and intraperitoneal administration.1992 · 58 citations
3International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome1997 · 1,270 citations
4Determination of vitamins a and e in serum and plasma using a simplified clarification method and high-performance liquid chromatography1985 · 132 citations
5Frataxin is Reduced in Friedreich Ataxia Patients and is Associated with Mitochondrial Membranes1997 · 741 citations

Antioxidant Treatment of Patients With Friedreich Ataxia | Synapse