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January 22, 2008Open Access

HLA class I supertypes: a revised and updated classification

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Resumen

As a result of this updated analysis, HLA supertype associations have been defined for over 750 different HLA-A and -B alleles. This information is expected to facilitate epitope identification and vaccine design studies, as well as investigations into disease association and correlates of immunity. In addition, the approach utilized has been made more transparent, allowing others to utilize the classification approach going forward.

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Cite This Study

Sidney et al. (Tue,) studied this question.

synapsesocial.com/papers/69dcc8b77873f5f05b134007 https://doi.org/https://doi.org/10.1186/1471-2172-9-1

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Binding of a peptide antigen to multiple HLA alleles allows definition of an A2-like supertype.1995 · 208 citations
2Identifiying Human MHC Supertypes Using Bioinformatic Methods2004 · 131 citations
3A framework to sub-type HLA supertypes2005 · 45 citations
4Identification of New Epitopes from Four Different Tumor-Associated Antigens: Recognition of Naturally Processed Epitopes Correlates with HLA-A∗0201-Binding Affinity2001 · 134 citations
5Identification of <i>Plasmodium falciparum</i> antigens by antigenic analysis of genomic and proteomic data2003 · 239 citations

HLA class I supertypes: a revised and updated classification | Synapse