January 1, 2019Open Access

Effects of dexmedetomidine on the RhoA /ROCK/ Nox4 signaling pathway in renal fibrosis of diabetic rats

JCJihua ChenCentral South University CCChen CaiSun Yat-sen University BXBao Xubin

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Resumen

Dex is possible to inhibit the expression of α-SMA and renal fibrous substance deposition in rat kidney via RhoA/ROCK/Nox4 signaling pathway, thereby reducing early kidney damage in model rats.

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Chen et al. (Tue,) studied this question.

synapsesocial.com/papers/69dcca31c099bcfdbb133b16 https://doi.org/https://doi.org/10.1515/med-2019-0105

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