September 10, 2020Open Access

A New Self-Healing Hydrogel Containing hucMSC-Derived Exosomes Promotes Bone Regeneration

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Resumen

A self-healing CHA/SF/GCS/DF-PEG hydrogel was successfully prepared. The hydrogel has excellent comprehensive properties and is expected to become a new type of bone graft material. This hydrogel has the effect of promoting bone repair, which is more significant after the addition of hucMSC-derived exosomes.

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Wang et al. (Thu,) studied this question.

synapsesocial.com/papers/69dd09a1854f360ad63597ea https://doi.org/https://doi.org/10.3389/fbioe.2020.564731

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1Rabbit Articular Cartilage Defects Treated With Autologous Cultured Chondrocytes1996 · 440 citations
2Augmented Bone Regeneration Activity of Platelet-Rich Plasma by Biodegradable Gelatin Hydrogel2005 · 136 citations
3Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes2014 · 289 citations
4Adipogenic RNAs are transferred in osteoblasts via bone marrow adipocytes-derived extracellular vesicles (EVs)2015 · 65 citations
5Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells2016 · 207 citations

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