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Age-Related Changes in Thyroid Function: A Longitudinal Study of a Community-Based Cohort | Synapse

February 17, 2012Open Access

Age-Related Changes in Thyroid Function: A Longitudinal Study of a Community-Based Cohort

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Resumen

Aging is associated with increased serum TSH concentrations, with no change in free T(4) concentrations. The largest TSH increase is in people with the lowest TSH at baseline. This suggests that the TSH increase arises from age-related alteration in the TSH set point or reduced TSH bioactivity rather than occult thyroid disease.

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Cite This Study

Bremner et al. (Fri,) studied this question.

synapsesocial.com/papers/69dd2d2c0644c7b49d40c4aa https://doi.org/https://doi.org/10.1210/jc.2011-3020

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Tobacco Smoking and Thyroid Function2007 · 198 citations
2Narrow Individual Variations in Serum T<sub>4</sub>and T<sub>3</sub>in Normal Subjects: A Clue to the Understanding of Subclinical Thyroid Disease2002 · 648 citations
3Age and secular trends in risk factors for cardiovascular disease in Busselton1995 · 67 citations
4Clinical Significance of Measurements of Antithyroid Antibodies in the Diagnosis of Hashimoto's Thyroiditis: Comparison with Histological Findings1996 · 96 citations
5Age- and Race-Based Serum Thyrotropin Reference Limits2009 · 259 citations