October 20, 2020Open Access

Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer

Puntos clave

Los puntos clave no están disponibles para este artículo en este momento.

Resumen

This model is the first immunocompetent mouse model similar to TME of human clinical PM with fibrosis. By using this model, new treatment strategies for PM, such as anti-CAFs therapies, may be developed.

Me gusta

Guardar

Ver artículo completo

Cite This Study

Fujimori et al. (Tue,) studied this question.

synapsesocial.com/papers/69dd32eda6ead7ee0940c615 https://doi.org/https://doi.org/10.1186/s12885-020-07477-x

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Cancer-Associated Fibroblasts Affect Intratumoral CD8+ and FoxP3+ T Cells Via IL6 in the Tumor Microenvironment2018 · 390 citations
2Activated gastric cancer-associated fibroblasts contribute to the malignant phenotype and 5-FU resistance via paracrine action in gastric cancer2018 · 38 citations
3Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer2015 · 9,460 citations
4Fibrosis in the peritoneum induced by Scirrhous gastric cancer cells may act as “soil” for peritoneal dissemination1996 · 86 citations
5Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries2018 · 87,726 citations

Me gusta

Guardar

Ver artículo completo