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Preexposure Prophylaxis for the Prevention of HIV Infection | Synapse

June 11, 2019Open Access

Preexposure Prophylaxis for the Prevention of HIV Infection

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Resumen

In adults at increased risk of HIV infection, PrEP with oral tenofovir disoproxil fumarate monotherapy or tenofovir disoproxil fumarate/emtricitabine was associated with decreased risk of acquiring HIV infection compared with placebo or no PrEP, although effectiveness decreased with suboptimal adherence.

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Cite This Study

Chou et al. (Tue,) studied this question.

synapsesocial.com/papers/69dd3f7f7d97b7e86940c6ae https://doi.org/https://doi.org/10.1001/jama.2019.2591

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Updated Guidelines for Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV—United States, 20162016 · 125 citations
2Measuring inconsistency in meta-analyses2003 · 62,840 citations
3Daily and non-daily pre-exposure prophylaxis in African women (HPTN 067/ADAPT Cape Town Trial): a randomised, open-label, phase 2 trial2017 · 118 citations
4Adherence to Pre-Exposure Prophylaxis for HIV Prevention in a Clinical Setting2016 · 80 citations
5Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study2014 · 1,252 citations