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Biomarkers and Disease Severity in Children With Community-Acquired Pneumonia | Synapse

May 13, 2020Open Access

Biomarkers and Disease Severity in Children With Community-Acquired Pneumonia

TFTodd A. FlorinNorthwestern University LALilliam AmbroggioChildren's Hospital Colorado CBCole BrokampCincinnati Children's Hospital Medical Center

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Resumen

WBC count, ANC, CRP, and procalcitonin are generally not useful to discriminate nonsevere from severe disease in children with CAP, although CRP and procalcitonin may have some utility in predicting the most severe outcomes.

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Cite This Study

Florin et al. (Wed,) studied this question.

synapsesocial.com/papers/69dd449e0644c7b49d40c871 https://doi.org/https://doi.org/10.1542/peds.2019-3728

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Usefulness of Procalcitonin Levels in Community-Acquired Pneumonia According to the Patients Outcome Research Team Pneumonia Severity Index2005 · 187 citations
2A simulation study of the number of events per variable in logistic regression analysis1996 · 9,152 citations
3Procalcitonin and the Calcitonin Gene Family of Peptides in Inflammation, Infection, and Sepsis: A Journey from Calcitonin Back to Its Precursors2004 · 571 citations
4Identifying Pediatric Severe Sepsis and Septic Shock: Accuracy of Diagnosis Codes2015 · 62 citations
5Efficacy of serum procalcitonin in evaluating severity of community-acquired pneumonia in childhood2007 · 77 citations