Does BNP/NT-proBNP or direct echocardiography improve the diagnosis of heart failure in primary care compared to ECG or preliminary investigation?
For diagnosing heart failure in primary care, BNP or NT-proBNP should be prioritized over ECG, and direct echocardiography may be appropriate for some patients, challenging current NICE recommendations.
The analysis suggests the need for important changes to the NICE recommendations. First, BNP (or NT-proBNP) should be recommended over ECG and, second, some patients should be referred straight for echocardiography without undergoing any preliminary investigation. Future work should include evaluation of the clinical rule described above in clinical practice.
Mant et al. (Wed,) studied this question.
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