Body roundness index and the risk of knee osteoarthritis: evidence from the China Health and Retirement Longitudinal Study

This study establishes that an increase in BRI significantly elevates KOA risk. These findings suggest that BRI could be an effective tool for KOA risk assessment and could contribute to the development of personalized prevention strategies. Additionally, BRI is valuable in elucidating the potential mechanisms linking body fat distribution and inflammatory responses in KOA progression.