October 20, 2011

Deregulation of Hippo kinase signalling in Human hepatic malignancies

HLHua LiHenan University AWAndy WolfeUniversity of Kansas SSSeth SepterChildren's Hospital Colorado

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Resumen

These data show that Yap induction mediated by inactivation of Lats is observed in hepatic malignancies. These studies highlight Hippo kinase pathway as a novel therapeutic target for hepatic malignancies.

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Li et al. (Thu,) studied this question.

synapsesocial.com/papers/69df1b23d9e0feb21c5919da https://doi.org/https://doi.org/10.1111/j.1478-3231.2011.02646.x

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