What question did this study set out to answer?

To assess the effectiveness of medication review and deprescribing interventions on prescribing appropriateness and clinical outcomes in older residents of long-term care facilities.

April 15, 2026Open Access

Evaluating the impact of medication review and deprescribing on prescribing appropriateness and clinical outcomes in older people residing in long-term care facilities: a systematic review and meta-analysis

Puntos clave

To assess the effectiveness of medication review and deprescribing interventions on prescribing appropriateness and clinical outcomes in older residents of long-term care facilities.
Conducted a systematic review and meta-analysis of relevant studies.
Focused on older adults living in long-term care facilities (LTCF) with polypharmacy.
Evaluated the impact on prescribing appropriateness and clinical outcomes, including falls and hospitalisations.
Medication review interventions improved prescribing appropriateness in older LTCF residents.
No significant impact on clinical outcomes like falls, hospitalizations, and mortality was found.

Resumen

Comprehensive medication review interventions improved prescribing appropriateness in older LTCF residents with polypharmacy but did not significantly affect clinical outcomes (i.e. falls, hospitalisations and mortality). Further high-quality studies using standardised approaches are needed.

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