Current challenges in the development of liposomes to target mitochondria

Puntos clave

• The central aim is to explore the challenges faced in developing liposomes for targeted mitochondrial delivery.
• Review of current literature on liposomes and their delivery mechanisms to mitochondria
• Analysis of factors affecting delivery efficiency and safety
• Discussion of hypotheses that need further investigation
• Clinical translation of mitochondria-targeted liposomes remains unachieved
• Key factors affecting delivery include surface chemistry and ligand density
• Understanding intracellular trafficking is essential for improving delivery safety and efficiency

Resumen