December 19, 2018

Analysis of 307 cases with drug‐induced liver injury between 2010 and 2018 in Japan

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Resumen

Japanese DILI patients are somewhat different from those of Europe and North America. The diagnostic scale of the DDW-Japan 2004 workshop has been used in Japan. However, there are many issues to improve the causality assessment of DILI that we must investigate in the future. It is critical to elucidate the mechanisms of drug metabolism and the pathophysiology of liver injury by various drugs to prevent DILI.

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Aiso et al. (Wed,) studied this question.

synapsesocial.com/papers/69df4dbb4fb243fc8e591e43 https://doi.org/https://doi.org/10.1111/hepr.13288

Also Consider

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1Drug‐induced liver injury in Japan: An analysis of 1676 cases between 1997 and 20062009 · 138 citations
2Fundamental studies on the lymphocyte stimulation test in patients with drug-induced allergic hepatic injury.1989 · 9 citations
3Causality assessment of adverse reactions to drugs—I. A novel method based on the conclusions of international consensus meetings: Application to drug-induced liver injuries1993 · 1,481 citations
4[Clinical characteristics of acute toxic liver injury].2004 · 19 citations
5Drug‐induced liver injury at an Asian center: a prospective study2007 · 151 citations

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