Detection of a Single Nucleotide Polymorphism Using Single‐Walled Carbon‐Nanotube Near‐Infrared Fluorescence

The detection of a single nucleotide polymorphism (SNP) using single-walled carbon nanotube (SWNT) fluorescence is demonstrated for SWNTs coated in a probe DNA sequence (see image) via a fluorescence-energy increase of only 0.8 meV upon addition of the complement containing a SNP. This mechanism is simple, label- and enzyme-free, and the properties of the probe DNA that enable this detection are examined. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.