September 6, 2016Open Access

Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis

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Resumen

Our data suggest that the SHH signalling pathway plays an important role in MB. GLI is an oncogenic transcription factor in the SHH pathway, and targeting GLI with GANT61 results in favourable antitumour activity and targeted therapy.

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Lin et al. (Tue,) studied this question.

synapsesocial.com/papers/69e12c8a9e97a987877cb252 https://doi.org/https://doi.org/10.1007/s00432-016-2241-1

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