What question did this study set out to answer?

Investigate the presence of tigecycline resistance gene tet(X4) in E. coli associated with IBS-D.

April 19, 2026Journal of Global Antimicrobial Resistance0 citationsOpen Access

Plasmid-mediated tigecycline resistance gene tet(X4) in Escherichia coli from patients with diarrhea-predominant irritable bowel syndrome

XWXuan WuBeijing Center for Disease Prevention and Control GCGuorong ChenBeijing Anzhen Hospital LYLu Yang

Puntos clave

Investigate the presence of tigecycline resistance gene tet(X4) in E. coli associated with IBS-D.
Sample collection from IBS-D patients
Molecular analysis to detect tet(X4) gene
Plasmid characterization for mobility and diversity
First evidence of tet(X4)-carrying E. coli in IBS-D patients
Diverse plasmid profiles associated with tet(X4)
Need for enhanced surveillance of resistance in clinical settings

Resumen

This study provides the first evidence of tet(X4)-carrying E. coli in IBS-D patients and highlights the diversity and mobility of associated plasmids. These findings underscore the need for continued surveillance of plasmid-mediated tigecycline resistance in clinical gastrointestinal populations.

Preguntar a la IA

Me gusta

Guardar

Ver artículo completo