Healthy sleep, proteomic signatures, and incident depression: associations accounting for genetic risk in an adult cohort

Puntos clave

• This research aims to explore the connections between healthy sleep, proteomic profiles, and the risk of depression, while considering genetic influences.
• Analyzed plasma proteomic data from an adult cohort
• Examined sleep patterns and their quality
• Evaluated the association with depression incidence
• Controlled for genetic risk factors
• Healthy sleep patterns correlate with distinct proteomic signatures
• Participants with healthier sleep showed lower rates of depression
• Proteomic data indicate potential biomarkers for depression prevention
• Genetic risk factors modulated the associations observed