Do very low calorie diets improve diastolic dysfunction in patients with obesity?
Very low calorie diets may serve as a potential therapeutic intervention for diastolic dysfunction in obesity and diabetes, despite a transient initial decline in ventricular function.
Whilst VLCDs result in dramatic improvements in insulin resistance, they are associated with transient but significant cardiovascular functional decline, which may have an impact on those with the coexisting cardiac disease. However, after 8 weeks, the diet was associated with normalisation of cardiac function, suggesting they may form a potential therapeutic intervention for diastolic dysfunction in obesity and diabetes.
Rayner et al. (Wed,) studied this question.
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