What question did this study set out to answer?

To discuss a rare case of widespread vasculitis characterized by giant cells in small and medium-sized arteries and veins.

April 21, 2026Open Access

A rare widespread vasculitis with giant cells in small- and medium-sized arteries and veins

Puntos clave

To discuss a rare case of widespread vasculitis characterized by giant cells in small and medium-sized arteries and veins.
Clinical examination and history collection from the patient
Skin biopsy analysis to determine the nature of the inflammatory process
Contrast-enhanced computed tomography (CT) to assess vascular involvement
Initial C-reactive protein (CRP) levels were high at 16.5 mg/dL, indicating inflammation.
Treatment with diaphenylsulfone resulted in a significant drop in CRP to 0.5 mg/dL.
Associated symptoms such as the rash resolved after treatment.

Resumen

A woman in her 70s presented with low-grade fevers and painful subcutaneous nodules on both thighs 1 year ago.A skin biopsy revealed an inflammatory cell infiltrate with fibrin thrombi in small arteries.A tentative diagnosis of polyarteritis nodosa was made.Contrast-enhanced computed tomography (CT) showed no vascular inflammation.She was treated with diaphenylsulfone, after which the rash resolved and C-reactive protein (CRP) fell from 16.5 to 0.5 mg/dL.

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