Sustainable and effective medicinal treatments have entered a new age with the advent of Nanotechnology (NT) and green chemistry. By harnessing the bioactive characteristics of phytochemicals obtained from plants, plant-based production of silver nanoparticles (AgNPs) provides a safer, more economical, and less harmful alternative to traditional physical and chemical procedures. This review summarizes the main processes, phytochemical interactions, and morphological aspects that are prerequisites for the generation of plants-mediated AgNPs, which could reveal their revolutionary potential. Their unique physicochemical characteristics and biocompatibility prove the superlative antibacterial, anti-inflammatory, antiviral, antifungal, and anticancer activities of such AgNPs. In the spirit of green chemistry, these nanoparticles minimise the impact on environmental terms, thus showing a better therapeutic effectiveness. Among other examples of their versatility in modern medicine, their newly developed applications are in diagnostic imaging, targeted medication, and wound healing. This is a review of the fundamental processes, phytochemical interactions, and morphological aspects that are prerequisites for the generation of plant-mediated AgNPs, which could reveal their revolutionary potential. Their unique physicochemical characteristics and biocompatibility demonstrate the superlative antibacterial, anti-inflammatory, antiviral, antifungal, and anticancer activities of these AgNPs. In the spirit of green chemistry, these nanoparticles minimise environmental impact, thereby demonstrating better therapeutic effectiveness. Among other examples of their versatility in modern medicine, their newly developed applications include diagnostic imaging, targeted medication, and wound healing. Modern advances in synthesis methods, characterisation tools, and therapeutic uses are discussed in this article, with a focus on how plant diversity might be used to customize the activity of NPs. The article highlights how plant diversity can be used to customise nanoparticle functionality and discusses the opportunities and challenges of translating herbal AgNPs into clinical personalised medicine. The use of plant-based AgNPs signifies a significant change in thinking about sustainable nanomedicine, as they combine the best of both traditional herbal medicines and modern NT.
Sagar et al. (Tue,) studied this question.