Enhanced bone regeneration and cellular protection from oxidative stress using a vitamin C-based scaffold.
Puntos clave
To evaluate the effectiveness of a vitamin C-based scaffold in promoting bone regeneration and protecting cells from oxidative stress.
Developed a VitC@HAP-HYA composite scaffold with multifunctional properties.
Assessed bioactivity and osteogenic potential through in vitro analysis.
Evaluated cytoprotective features against oxidative stress.
The composite showed superior bioactivity compared to traditional scaffolds.
It significantly increased osteogenic potential, enhancing bone cell growth.
Cytoprotective effects were observed, indicating reduced cell damage from oxidative stress.
Resumen
The VitC@HAP-HYA composite effectively combines multifunctional qualities, demonstrating superior bioactivity, increased osteogenic potential, and vital cytoprotective features. These results robustly endorse its potential as a sophisticated framework for bone tissue engineering, including applications such as anti-cancer bone excision repair.
Immunomodulation and Oxidative Stress Mitigation Mediate Enhanced Bone Regeneration by a Platelet‐Rich Plasma‐Loaded Composite Scaffold2026 · 2 citations