Highlights of eosinophilic chronic rhinosinusitis with nasal polyps in definition, prognosis, and advancement

Sinonasal tissue eosinophilia is present in a majority of CRSwNP patients but is currently more common in the West than in the East. Cutoff values of eosinophils as the diagnostic criteria of eosinophilic CRSwNP are subject to change with geographic and ethnic differences over time. It will be important to identify validated eosinophil-related biomarkers in different continents/countries for future research and for the introduction of precision medicine.