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Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis | Synapse

February 7, 2018Open Access

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Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis

RSRon ShahUniversity of Ottawa MSMikhail S. ShchepinovCentre National de la Recherche Scientifique DPDerek A. PrattUniversity of Stuttgart

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Resumen

contribute to the cellular pool of lipid hydroperoxides that initiate ferroptosis, but lipid autoxidation drives the cell death process.

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Cite This Study

Shah et al. (Wed,) studied this question.

synapsesocial.com/papers/69f8689c7dd5773993f77c00 https://doi.org/https://doi.org/10.1021/acscentsci.7b00589