Copper-nanoparticle-embedded hydrogel for killing bacteria and promoting wound healing with photothermal therapy

could stimulate NIH-3T3 fibroblast proliferation without any inflammatory responses. Moreover, chronic wound healing process of S. aureus-infected model was significantly accelerated with prominent antibacterial ability, reduced inflammatory response, and promoted angiogenesis ability in vivo. In summary, Cu-NP-embedded hydrogels are a promising candidate for skin tissue regeneration and potentially valuable for clinical applications.