BACKGROUND: Ozonated olive oil, a potent antimicrobial and healing agent, has gained attention in pediatric dentistry for its role in enhancing postextraction socket healing. Both combining the therapeutic effects of ozone and olive oil, it promotes tissue regeneration, reduces inflammation, and minimizes the need for systemic antibiotics and analgesics. Its noninvasive, biocompatible nature makes it particularly suitable for children, ensuring faster recovery with fewer complications, representing a promising advancement in pediatric postoperative care. AIM: To assess the efficacy of ozonated olive oil on postextraction healing. SUBJECTS AND METHODS: A prospective study was conducted on 100 patients who required dual extractions. Primary molars were selected, and extraction sites were chosen randomly first for the ozone therapy group and then for the control group. Patients were followed up on the 3 rd and 7 th day postoperative for evaluation of wound healing using the Healing index of Landry, Turnbull, and Howley, pain using the Visual Analog Scale (VAS) after 6 h and 24 h, and hemostasis using a stopwatch. STATISTICAL ANALYSIS USED: Postoperative wound healing scores were recorded on an ordinal scale. RESULTS: Postoperatively, VAS scores for pain in Group A were significantly lower than those in Group B after 6 h and 24 h. According to the Landry, Turnbull, and Howley Index, at 3rd and 7th day, post-operative wound healing score in group A was significantly higher than those in Group B. Haemostasis time in group A was significantly shorter than Group B. CONCLUSIONS: Ozonated olive oil may be used as a safe and effective alternative to conventional painkillers and antibiotics. Antibiotics in pediatric dentistry should be used judiciously to prevent resistance and unnecessary side effects.
Jain et al. (Sun,) studied this question.