Does a prolonged S-wave upstroke in V1 through V3 distinguish ARVD/C from RVOT tachycardia and normal controls?
A prolonged S-wave upstroke >=55 ms in V1-V3 is a highly prevalent ECG marker that helps distinguish ARVD/C from RVOT tachycardia.
BACKGROUND: The purpose of this study was to systematically study diagnostic and prognostic electrocardiographic (ECG) characteristics of arrhythmogenic right ventricle dysplasia/cardiomyopathy (ARVD/C). METHODS AND RESULTS: The patient population included 50 patients with ARVD/C (27 males, 23 females; mean age 38+/-15 years). We also analyzed the ECG of 50 age- and gender-matched normal control subject and 28 consecutive patients who presented with right ventricular outflow tract (RVOT) tachycardia. Right bundle-branch block (RBBB) was present in 11 patients (22%). T-wave inversions in V1 through V3 were observed in 85% of ARVD/C patients in the absence of RBBB compared with none in RVOT and normal controls, respectively (P or =110 ms in V1 through V3 was present in 64% of patients. Among those without RBBB, our newly proposed criterion of "prolonged S-wave upstroke in V1 through V3" > or =55 ms was the most prevalent ECG feature (95%) and correlated with disease severity and induction of VT on electrophysiological study. This feature also best distinguished ARVD/C (diffuse and localized) from RVOT. CONCLUSIONS: A prolonged S-wave upstroke in V1 through V3 is the most frequent ECG finding in ARVD/C and should be considered as a diagnostic ECG marker.
Nasir et al. (Mon,) studied this question.
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